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Updated: Oct 11, 2025

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Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9
Published on: January 3, 2015
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Towards precise large genomic fragment deletion
1Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Trends in Genetics : TIG
|December 7, 2021
Abstract:
The prime editing (PE) system can install small insertions and deletions in addition to various base substitutions. Two recent studies published in Nature Biotechnology by Choi et al. and Jiang et al. report that the system can also be tweaked for efficient and precise deletions of large DNA fragments.

