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MULTIPLE INTERVAL DEBULKING SURGERY IN RECURRENT UTERINE SARCOMA (CASE REPORT).
S Chetverikov1, V Maksymovskyi1, D Atanasov1
1Center of Reconstructive and Renovative Medicine (University Clinic) of Odesa National Medical University, Surgery Department №3, Ukraine.
Georgian Medical News
|December 13, 2021
Summary
Aggressive cytoreductive surgery offers long-term survival for uterine sarcoma patients with recurrent disease. This approach, involving extensive tumor removal, significantly improves quality of life and extends life expectancy.
Area of Science:
- Gynecologic Oncology
- Surgical Oncology
- Oncologic Imaging
Background:
- Uterine sarcoma presents a significant challenge due to its propensity for recurrence and resistance to conventional therapies.
- Multiple relapses necessitate aggressive treatment strategies to manage advanced disease and improve patient outcomes.
Observation:
- A 61-year-old woman with recurrent uterine sarcoma underwent 13 cytoreductive surgeries, including extensive organ resections and hyperthermic intraperitoneal chemotherapy.
- Despite extensive tumor debulking (over 60 liters), the patient maintained a satisfactory quality of life and continued working as a teacher.
- Serial computed tomography scans showed no signs of tumor recurrence 64 months post-relapse.
Findings:
- The patient achieved an overall survival of 69 months, surpassing the 5-year mark from initial diagnosis.
- Repeated optimal cytoreduction, maximizing tumor mass removal and restoring organ integrity, is crucial for managing chemo- and radioresistant abdominal tumors.
- This surgical approach mitigates complications like cachexia, intoxication, and organ dysfunction, thereby prolonging survival.
Implications:
- Cytoreductive surgery is a vital treatment modality for recurrent uterine sarcoma, offering a survival benefit beyond standard therapies.
- Aggressive surgical management can significantly enhance the quality of life for patients with advanced and recurrent gynecologic malignancies.
- This case highlights the potential of maximal cytoreduction in achieving long-term disease control and improved survival in challenging uterine sarcoma cases.
