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Updated: Oct 10, 2025

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Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
Published on: December 8, 2023
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Engineering an Au nanostar-based liquid phase interfacial ratiometric SERS platform with programmable entropy-driven
Guanli Fan1, Xiaorong Gao1, Shuling Xu1
1Department of Chemistry, Liaocheng University, Liaocheng, 252059, Shandong, China. xueqingwang1983@163.com.
Abstract:
Developing sensing platforms that simultaneously integrate high sensitivity and accuracy has been a promising but challenging task for the detection of protein biomarkers in clinical samples. Herein, we engineered an Au nanostar-based liquid phase interfacial ratiometric SERS platform with programmable entropy-driven DNA circuits to detect the protein biomarker Mucin 1 (MUC1) in clinical samples.

