Related Experiment Video
Updated: Oct 10, 2025
05:36
Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
7.9K
Predictive Factors for Cardiopulmonary Resuscitation Failure
Ardi Pramono1, Yunita Widyastuti2, Yati Soenarto3
1Department of Anesthesiology, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia.
Indian Journal of Palliative Care
|December 13, 2021
Summary
Predictive factors for cardiopulmonary resuscitation (CPR) failure in chronic disease patients include sepsis, male gender, acidosis, and asystole. These factors significantly increase the likelihood of unsuccessful resuscitation efforts in this vulnerable population.
Area of Science:
- Emergency Medicine
- Critical Care Medicine
- Cardiology
Background:
- Patients with chronic diseases frequently present to emergency departments with critical conditions like dyspnea and cardiac arrest.
- Cardiopulmonary resuscitation (CPR) is a critical intervention for cardiac arrest, but success rates vary, especially in patients with underlying chronic conditions.
Purpose of the Study:
- To identify key predictive factors associated with CPR failure in patients diagnosed with chronic diseases.
- To improve risk stratification and inform clinical decision-making for CPR in this patient group.
Main Methods:
- A cross-sectional study analyzed medical records from a primary healthcare center in Yogyakarta (2017-2019).
- Bivariate analysis using Fisher's exact test identified relative risks.
- Multivariate logistic regression with backward elimination determined odds ratios (OR) for significant predictors (P < 0.25).
Main Results:
- Sepsis was identified as a primary predictor of CPR failure.
- Male gender (OR 9.1), acidosis (OR 8.1), and asystole heart rhythm (OR 7.8) were significantly associated with increased odds of CPR failure (P < 0.05).
- These factors collectively indicate a high likelihood of resuscitation failure in affected patients.
Conclusions:
- Sepsis, male gender, acidosis, and asystole are significant determinants of mortality in chronic disease patients undergoing CPR.
- Developing predictive scoring systems or checklists using these factors could aid in determining CPR success likelihood.
- Further validation with data from other institutions is recommended to refine predictive models.
Related Concept Videos
01:21Cardiopulmonary Resuscitation I: Adult
160
Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...
160
01:25Cardiopulmonary Resuscitation IV: Pharmacological Management
106
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
106
01:23Cardiopulmonary Resuscitation III: AED Use
112
Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
112
01:21Acute Respiratory Failure-II
422
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
422
01:27Heart Failure I: Introduction
124
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
124
01:30Acute Respiratory Failure-III
377
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
377