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Cannabidiol (CBD) Use among children with juvenile idiopathic arthritis
Christopher J Failing1,2,3, Kevin F Boehnke4,5, Meredith Riebschleger6,7
1Department of Pediatric Rheumatology, C.S. Mott Children's Hospital, Ann Arbor, United States, MI. chris.failing@gmail.com.
Insights
Caregivers of children with juvenile idiopathic arthritis (JIA) show interest in cannabidiol (CBD) despite infrequent use. More research and education are needed regarding CBD safety and efficacy for JIA management.
Area of Science:
- Pediatric Rheumatology
- Cannabinoid Therapeutics
- Patient Caregiver Attitudes
Background:
- Juvenile idiopathic arthritis (JIA) presents significant treatment challenges.
- Cannabidiol (CBD) is increasingly accessible, yet its application in JIA remains unstudied.
- Caregiver perspectives on CBD for JIA are largely unknown.
Purpose of the Study:
- To investigate caregiver knowledge, attitudes, and interest in using cannabidiol (CBD) for juvenile idiopathic arthritis (JIA).
- To assess current CBD usage patterns and information sources among caregivers of JIA patients.
- To identify gaps in communication between caregivers and healthcare providers regarding CBD for JIA.
Main Methods:
- Retrospective chart review of JIA patients (2017-2019) at a Midwestern institution.
- Anonymous online survey distributed to primary caregivers of JIA patients.
- Descriptive statistical analysis comparing caregivers with varying levels of interest in CBD.
Main Results:
- Of 136 surveyed caregivers, 34.5% expressed no interest in CBD, while 54% contemplated and 7% currently used CBD for their child's JIA.
- Information on CBD primarily came from television (70%) or friends (50%), not rheumatologists (2%).
- Most caregivers had not discussed CBD with their child's rheumatologist; current users often lacked knowledge of CBD dosage.
Conclusions:
- A significant caregiver interest in CBD for JIA exists, contrasting with current low usage rates.
- The lack of rheumatologist involvement and limited caregiver knowledge highlight a critical need for improved education.
- Further research into the safety and efficacy of CBD for pediatric JIA is warranted.
Background:
Juvenile idiopathic arthritis (JIA) is common and difficult to treat. Cannabidiol (CBD) is now widely available, but no studies to date have investigated the use of CBD for JIA.
Methods:
We performed a chart review to identify patients with JIA at a Midwestern medical institution between 2017 and 2019. We surveyed primary caregivers of JIA patients using an anonymous, online survey with questions on caregiver knowledge and attitudes towards CBD. We compared respondents with no interest in CBD use vs. those contemplating or currently using CBD using descriptive statistics.
Results:
Of 900 reviewed charts, 422 met inclusion criteria. Of these, 236 consented to be sent a survey link, and n=136 (58%) completed surveys. Overall, 34.5% (n=47) of respondents reported no interest in using a CBD product for their child's JIA, while 54% (n=79) reported contemplating using CBD and 7% (n=10) reported currently giving their child CBD. Only 2% of respondents contemplating or actively using a CBD product learned about CBD from their child's rheumatologist, compared with television (70%) or a friend (50%). Most respondents had not talked to their child's rheumatologist about using CBD. Of those currently using CBD, most used oral or topical products, and only 10% of respondents (n=1) knew what dose they were giving their child.
Conclusions:
Our results show infrequent use but a large interest in CBD among caregivers of children with JIA. Given CBD's unknown safety profile in children with JIA, this study highlights a need for better studies and education around CBD for pediatric rheumatologists.
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