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Cranial and Spinal Meninges01:19

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
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Related Experiment Video

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Multisegment Intradural Extramedullary Ependymoma.

Rishika Trivedi1,2, Pankaj Trivedi3

  • 1Medicine, Himalayan Institute of Medical Sciences, Dehradun, IND.

Cureus
|December 15, 2021
PubMed
Summary
This summary is machine-generated.

This study reports a rare, large intradural extramedullary ependymoma in a young patient. The tumor, originating from the conus medullaris, was WHO grade II, an uncommon finding for this spinal location.

Keywords:
conus medullarisintradural extramedullary spine tumorslaminectomylow back painspinal ependymoma

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Area of Science:

  • Neuro-oncology
  • Spinal cord tumors
  • Neurosurgery

Background:

  • Ependymomas typically occur intradurally and intramedullarily, often at the conus medullaris or filum terminale.
  • Intradural extramedullary spinal tumors are less common than intramedullary types.
  • Spinal ependymomas are a subset of gliomas arising from ependymal cells within the central nervous system.

Observation:

  • A young patient presented with urinary retention and chronic radicular back pain.
  • Imaging identified a significant intradural ependymoma spanning from D11 to S1, measuring 21 cm.
  • The tumor, despite originating from the conus medullaris, exhibited an unusual histological grade.

Findings:

  • Histological analysis confirmed a World Health Organization (WHO) grade II ependymoma.
  • This grade is rare for ependymomas originating in the conus medullaris, with only 30% being non-myxopapillary.
  • Surgical resection was performed via D10 to S1 laminectomy.

Implications:

  • This case highlights the importance of considering rare presentations of spinal ependymomas.
  • Understanding the varied locations and grades of ependymomas is crucial for accurate diagnosis and treatment planning.
  • Further research into the specific characteristics and behavior of non-myxopapillary ependymomas in this location may be warranted.