Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The 2026 global roadmap for textile-integrated wearable technologies in health.

Physiological measurement·2026

Same author

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Biowaste-Derived Catalysts for Sustainable Electrochemical Water Splitting: A Pathway to Circular Bioeconomy.

ChemSusChem·2026

Same author

In silico investigation of the role of local and global inflammation-driven feedback in myelopoiesis and clonal cell expansion.

Journal of theoretical biology·2026

Same author

Comparison of 2D, 3D <i>In Vitro</i>, and <i>Ex Vivo</i> Platforms for Modeling the Rat Small Intestine.

Bioengineering (Basel, Switzerland)·2026

Same author

Bioelectronic Technology for Nutritional Research-a Novel In Vitro Platform for a Better Understanding of Human Gut Barrier Absorption.

Advanced biology·2026

Same journal

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Chemical reviews·2026

Same journal

Introduction to Semi-artificial Photosynthesis.

Chemical reviews·2026

Same journal

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026

Same journal

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026

Same journal

Ink Design for Printing Perovskite Solar Cells and Modules.

Chemical reviews·2026

Same journal

Advanced Single-Atom Catalysts for Thermal-Catalytic C1 Chemistry.

Chemical reviews·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Organic Bioelectronics for In Vitro Systems.

Charalampos Pitsalidis^1,2, Anna-Maria Pappa³, Alexander J Boys²

¹Department of Physics, Khalifa University of Science and Technology, P.O. Box 127788, Abu Dhabi 127788, UAE.

Chemical Reviews

|December 15, 2021

Summary

This summary is machine-generated.

Bioelectronics, particularly conjugated polymers, are advancing in vitro systems for drug discovery. These organic electronic materials enable precise biological monitoring and control, paving the way for next-generation diagnostic and toxicological testing.

More Related Videos

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

Published on: September 20, 2021

Related Experiment Videos

Last Updated: Jun 21, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

Published on: September 20, 2021

Area of Science:

Bioelectronics
Materials Science
Biomedical Engineering

Background:

Bioelectronics significantly improve clinical diagnostics and precision medicine.
The integration of bioelectronics with microfluidics and advanced in vitro models offers a path to reduce animal testing in drug discovery and toxicology.
Organic electronic materials, especially conjugated polymers, are well-suited for bioelectronic applications due to their biomimetic properties and processing versatility.

Purpose of the Study:

To review advances in conjugated polymers for in vitro bioelectronic interfacing.
To highlight the development of next-generation in vitro systems using conjugated polymers.
To discuss the potential and challenges of conjugated polymers for clinical translation of in vitro systems.

Main Methods:

Review of current literature on conjugated polymers in bioelectronics.
Showcasing in vitro interfacing across various biological models, from cellular components to 3D cultures.
Analysis of the state-of-the-art, possibilities, and challenges.

Main Results:

Conjugated polymers demonstrate significant potential for creating sophisticated in vitro bioelectronic systems.
Interfacing capabilities span multiple length scales and biological complexities.
Progress is being made in developing label-free monitoring and precise biological control.

Conclusions:

Conjugated polymers are key to advancing in vitro systems for drug discovery and toxicology.
Further development is needed for seamless clinical translation of these technologies.
Bioelectronics offer a promising future for reducing reliance on animal studies.