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Updated: Oct 9, 2025

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP
Published on: September 8, 2023
Loop-Mediated Isothermal Amplification as a Promising Method for Mass COVID-19 Diagnostics
J A Makarova1, K A Fomicheva2, A I Osipyants2,3
1Faculty of Biology and Biotechnology, Higher School of Economics National Research University, 101000 Moscow, Russia.
Abstract:
Real-time reverse-transcription polymerase chain reaction (RT-PCR) is currently the most popular method for early COVID-19 diagnostics. However, loop-mediated isothermal amplification (LAMP) is superior to real-time RT-PCR in rapidity and simplicity, since it does not require expensive laboratory equipment and trained personnel. LAMP-based diagnostic kits for COVID-19 testing already exist, but corresponding tests are not yet widely available. The method has great potential for mass application. Here, we discuss the technical and methodological aspects of its widespread adoption.
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