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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation,

Karen Aknin1, Alexis Bontemps1, Amaury Farce2

  • 1Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.

Journal of Enzyme Inhibition and Medicinal Chemistry
|December 22, 2021
PubMed

Keywords:
Thymidine phosphorylase inhibitormolecular dockingmulticomponent reactionspyrido[2,3-d]pyrimidinedionepyrimido[4,5-b]quinoline-2,4-dione

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