Effective propagation of various type D retroviruses in human lymphoblastoid Raji cells

Type D retroviruses belong to viruses which often have a low titer in virus-reproducing cell-systems. In search of better conditions for virus propagation, Raji cells (an EBV-genome carrying human B-cell line) were infected with different isolates of type D retroviruses. as demonstrated by electron microscopy all of the viruses showed a very good and stable virus production during long term cultivation on Raji cells.