Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

209
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
209
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

723
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
723
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

482
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
482
Observational Studies01:11

Observational Studies

10.0K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
10.0K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

287
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
287
Longitudinal Research02:20

Longitudinal Research

12.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Buffering effects of amusement and awe on stress responses: Behavioral, physiological, and neural response.

NeuroImage·2025
Same author

Activation mapping in multi-center retrospective rat sensory-evoked functional MRI datasets using a unified pipeline.

Imaging neuroscience (Cambridge, Mass.)·2025
Same author

Feature-Tracking Method Can Estimate Right Ventricular Contractile Properties in Rats With Pulmonary Hypertension.

Circulation reports·2025
Same author

Altered Cerebral Cortical Gyrification in Ferrets with Neonatal Exposure to the Bacterial Endotoxin, Lipopolysaccharide.

eNeuro·2025
Same author

Dynamic functional connectivity associated with prospective memory success in children.

Neuroimage. Reports·2025
Same author

The <i>RELN</i> heterozygous single-nucleotide polymorphism rs362691 increases the prefrontal cortical thickness and modulates systemizing-related autistic tendencies in typically developing children and adolescents.

Frontiers in neuroscience·2025
Same journal

Correction: Pramesthi et al. Evaluating the Impact of Indonesia's National School Feeding Program (ProGAS) on Children's Nutrition and Learning Environment: A Mixed-Methods Approach. <i>Nutrients</i> 2025, <i>17</i>, 3575.

Nutrients·2026
Same journal

Correction: Huang et al. Correlation Study Between Dietary Behaviors, Lifestyle, and Psychological Problems in Chinese Children Aged 3-7. <i>Nutrients</i> 2025, <i>17</i>, 176.

Nutrients·2026
Same journal

Association of Dietary Animal and Plant Protein Composition with All-Cause Mortality: 24-Year Population-Based Cohort Study.

Nutrients·2026
Same journal

Phytochemistry, Bioavailability, and Molecular Mechanisms Underlying Multitarget Anticancer Activity of <i>Aloe vera</i>.

Nutrients·2026
Same journal

A Comparison of the Interstitial and Blood Glucose Responses Following Consumption of Different Carbohydrate-Containing Beverages in Humans: A Randomised Controlled Trial.

Nutrients·2026
Same journal

Across Kingdoms: The Bacteriome, Mycobiome, and Virome in Autoimmune Diseases: Mechanistic Insights, Therapeutic Perspectives, and the Emerging Role of COVID-19.

Nutrients·2026
See all related articles

Related Experiment Video

Updated: Oct 8, 2025

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.8K

Diet and Dementia: A Prospective Study.

Hikaru Takeuchi1, Ryuta Kawashima1,2,3

  • 1Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan.

Nutrients
|December 28, 2021
PubMed
Summary
This summary is machine-generated.

Dietary patterns may influence dementia risk. High bread, moderate meat/fish, and low fruit/vegetable intake were linked to a slightly reduced dementia onset risk in European adults.

Keywords:
breaddementiadietfishfruitmeatvegetables

More Related Videos

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.2K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K

Related Experiment Videos

Last Updated: Oct 8, 2025

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.8K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.2K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K

Area of Science:

  • Nutritional Epidemiology
  • Neuroscience
  • Gerontology

Background:

  • Dietary patterns are increasingly recognized as potential modifiable factors influencing cognitive health.
  • The relationship between specific food groups and the risk of developing dementia remains an active area of research.
  • Existing hypotheses, such as the protective effects of the Mediterranean diet, warrant further investigation with large-scale cohort studies.

Purpose of the Study:

  • To investigate the association between the intake frequency of various food classes and the incidence of dementia.
  • To examine if specific dietary patterns, including intake of bread, meat, fish, vegetables, fruits, poultry, and cereals, correlate with dementia risk.
  • To evaluate findings in the context of established dietary recommendations for brain health.

Main Methods:

  • A longitudinal cohort study of European adults (middle to old aged at baseline) was analyzed.
  • Participants (approx. 340,000) were followed from 2006-2010 until 2018, excluding those with dementia at baseline or within 5 years.
  • Cox proportional hazard models assessed associations between food-frequency questionnaire data and incident dementia, adjusting for confounders.

Main Results:

  • High intake of bread was associated with a small but significant decrease in dementia onset risk.
  • Moderate intake of total meat and total fish also showed a similar association with reduced dementia risk.
  • Low intake of vegetables and fruits was linked to a decreased risk of dementia onset, contrary to some expectations.

Conclusions:

  • The study suggests that certain dietary components, like high bread consumption and low vegetable/fruit intake, may be associated with a reduced risk of dementia.
  • Findings indicate that poultry and cereal intake were not significantly associated with dementia risk.
  • The observed associations are largely inconsistent with the hypothesis that a Mediterranean diet is protective against subsequent incident dementia.