[Pathomorphology of malignant skin lymphomas]

Clinico-morphologic study of 52 biopsy samples from patients with primary lymphoproliferative skin diseases was performed. Criteria of differential diagnosis of these diseases are suggested based on the differentiation degree of lymphoid cells, their belonging to T and B cell immune systems, and the character of proliferation (poly- or monoclonal). Three morphologic variants of malignant skin lymphoma have been distinguished, (lymphoplasmocytic, prolymphocytic and immunoblastic) all of them being clinically and prognostically different. The so-called "primary reticulosis" of skin is considered as a reactive proliferation of lymphoid cells, that in a number of cases transforms into a malignant lymphoma.