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Acute ventilatory changes during i.v. induction of anaesthesia with thiopentone or propofol in man. Studies using
R M Grounds1, D L Maxwell, M B Taylor
1Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London.
British Journal of Anaesthesia
|September 1, 1987
Abstract:
We have compared the acute ventilatory changes during induction of anaesthesia with equipotent doses of thiopentone and propofol in 12 premedicated female patients. Using ventilatory inductance plethysmography we have shown that both agents depress respiration to a similar and significant degree (P less than 0.001). However, although the functional residual capacity was reduced in patients receiving propofol, it increased slightly after induction with thiopentone (P less than 0.05).