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Simulating scan formation in multimodal optical coherence tomography: angular-spectrum formulation based on ballistic
Alexander L Matveyev1, Lev A Matveev1, Aleksandr A Moiseev1
1Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences, 46 Ulyanov Str., Nizhny Novgorod, 603950, Russia.
Biomedical Optics Express
|January 10, 2022
Summary
We developed a fast, full-wave spectral model for optical coherence tomography (OCT) scan formation. This efficient model accurately simulates OCT scans, aiding in developing new processing methods for biomedical applications.
Area of Science:
- Biomedical Optics
- Computational Imaging
- Optical Coherence Tomography
Background:
- Optical Coherence Tomography (OCT) is crucial for biomedical imaging.
- Accurate simulation models are needed to advance OCT technology.
- Existing models often rely on approximations limiting their scope.
Purpose of the Study:
- To present a computationally efficient, full-wave spectral model for OCT scan formation.
- To enable accurate simulation of OCT scans without paraxial approximations.
- To facilitate the development of novel OCT data processing techniques.
Main Methods:
- Developed a full-wave spectral model for OCT simulation.
- Incorporated arbitrary phase-amplitude profiles for illuminating beams.
- Utilized ballistic scattering approximation without density or location limitations.
- Included wave decay, dispersion, noise, and scatterer motion.
Main Results:
- Demonstrated comparative simulations of OCT-scans for Bessel vs. Gaussian beams.
- Simulated the effects of arbitrary aberrations at tissue boundaries.
- Modeled various scatterer motions and their impact on OCT scans.
- Validated the model's flexibility and computational efficiency.
Conclusions:
- The developed model provides a powerful tool for studying OCT scan properties.
- Its efficiency and accuracy support the development of advanced OCT processing methods.
- This model can significantly contribute to various biomedical applications of OCT.
