Related Experiment Video
Updated: Oct 7, 2025

Evaluating Flight Performance and Eye Movement Patterns Using Virtual Reality Flight Simulator
Published on: May 19, 2023
To look or not to look during vaccination: A pilot randomized trial
Priyanjali Mithal1, Pamela Simmons2, Tessa Cornelissen2
1Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.
Advising patients to look away from the needle during vaccinations can reduce fear. This pilot study found looking away decreased fear, but did not affect pain. Further research is recommended.
Area of Science:
- Medical Research
- Clinical Trials
- Psychology
Background:
- Clinicians often advise patients to look away during vaccinations, but this lacks evidence.
- Fear and pain perception during vaccinations are significant patient concerns.
Purpose of the Study:
- To investigate if looking at or away from the needle impacts adult vaccination pain and fear.
- To provide evidence-based recommendations for vaccination procedures.
Main Methods:
- A pilot randomized controlled trial involving university students receiving influenza vaccinations.
- Participants were assigned to look at or away from the needle.
- Self-reported pain and fear levels were collected.
Main Results:
- Randomization to look away from the needle significantly reduced fear compared to looking at it.
- Pre-existing preference to look away also correlated with higher fear.
- No significant differences in pain perception were found based on looking allocation or preference.
- Females reported higher fear and pain than males.
Conclusions:
- Advising patients to look away from the needle appears to be an effective strategy for reducing vaccination-related fear.
- Larger trials with diverse populations are needed to confirm these findings.
Related Concept Videos
Blinding
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Bioavailability Study Design: Healthy Subjects Versus Patients
Vaccinations
Blind Procedures
Bias in Epidemiological Studies

