Related Experiment Video

Updated: Oct 7, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.1K

Strategies to Optimize Adherence in Patients with Mycosis Fungoides

Warren H Chan1, Daniel J Lewis2, Madeleine Duvic3

  • 1Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

Cells
|January 11, 2022
PubMed

Insights

Improving patient adherence to skin condition medications is crucial for treatment success. This study explores strategies to enhance adherence in cutaneous T-cell lymphoma (CTCL) patients, aiming to reduce treatment failure.

Area of Science:

  • Dermatology
  • Oncology
  • Pharmacology

Background:

  • Suboptimal patient adherence is a major cause of treatment failure in common skin conditions.
  • Adherence in cutaneous T-cell lymphoma (CTCL) patients remains largely unexamined.
  • Improving adherence in CTCL may significantly enhance treatment outcomes.

Purpose of the Study:

  • To explore the impact of patient adherence on treatment outcomes in CTCL.
  • To adapt and apply established dermatological adherence strategies to the CTCL patient population.
  • To provide practical examples for improving adherence in CTCL management.

Main Methods:

  • Review and adaptation of patient adherence strategies from general dermatology.
  • Application of these strategies to the specific context of CTCL treatment.
  • Development of concrete examples for clinical implementation.

Main Results:

  • Suboptimal adherence is a significant factor in treatment failure for CTCL patients.
  • Existing dermatological adherence strategies can be effectively applied to CTCL.
  • Small modifications in patient counseling can improve adherence.

Conclusions:

  • Enhancing patient adherence is a promising approach to optimize CTCL therapy.
  • Implementing tailored adherence strategies can reduce treatment failure in CTCL.
  • Focusing on adherence can lead to better therapeutic results for CTCL patients.
Keywords:
PUVAadherenceanchoringbrentuximab vedotincutaneous T-cell lymphomaframinginterferonloss aversionmechlorethaminemogamulizumabmycosis fungoidesnitrogen mustardpatient adherencepsoriasisromidepsintopical steroidsvorinostat

More Related Videos

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis06:39

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Published on: October 27, 2023

1.1K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.5K

Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
114
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
238
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
282
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.8K
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
228
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.2K