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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Gore Cardioform ASD device thrombus weeks after COVID-19 infection.

Liliam Aquino1, Juan Carlos Muniz2, Pablo Marcelo Laufer3

  • 1Department of Pediatrics, Nicklaus Children's Hospital, Miami, Florida, USA.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|January 12, 2022
PubMed
Summary

A rare thrombus formed on a device closing an atrial septal defect (ASD) after COVID-19. This case suggests a potential link between COVID-19 infection and device-related thrombosis in pediatric patients.

Keywords:
COVID-19atrial septal defectdevice-related endocarditisdevice-related thrombosistranscatheter closure

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pediatrics

Background:

  • Transcatheter closure is a common procedure for atrial septal defects (ASDs).
  • Device-related thrombosis and endocarditis are rare complications following ASD closure.
  • COVID-19 infection is associated with a hypercoagulable state and thrombotic events.

Observation:

  • A 14-year-old female presented with fever weeks after transcatheter ASD closure.
  • The patient had an asymptomatic COVID-19 infection prior to the procedure.
  • A thrombus was identified on the atrial septal defect closure device.

Findings:

  • The occurrence of device-related thrombosis is extremely rare after transcatheter ASD closure.
  • The patient's recent asymptomatic COVID-19 infection raises suspicion for a potential link.
  • A hypercoagulable state induced by COVID-19 may contribute to thrombus formation.

Implications:

  • This case highlights the potential for COVID-19 to influence thrombotic risk, even post-infection.
  • Clinicians should consider COVID-19-related hypercoagulability in patients with unexplained thrombosis after device implantation.
  • Further research is needed to understand the long-term thrombotic risks associated with COVID-19 in pediatric patients undergoing cardiac procedures.