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Related Experiment Video

Updated: Oct 6, 2025

Translational Rabbit Model of Chronic Cardiac Pacing

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Published on: January 6, 2023

Minimizing Device-Device Interactions Using Bipolar Pacemaker Leads in a Pediatric Patient.

Mohammad S Khan¹, Walter Hoyt¹, Christopher Snyder²

¹The Congenital Heart Collaborative, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, MS 6011, Cleveland, OH, 44106, USA.

Pediatric Cardiology

|January 13, 2022

Summary

This summary is machine-generated.

Phrenic nerve injury can cause cardiac issues, necessitating both diaphragm and cardiac pacemakers. This case study shows bipolar mode safely prevents device-device interaction in pediatric patients.

Keywords:

Cervical spinal cord injury Device–device interaction Diaphragmatic pacer Pacemaker

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Area of Science:

Cardiology
Neurology
Biomedical Engineering

Background:

Phrenic nerve injury disrupts autonomic nervous system (ANS) function, potentially causing bradycardic arrest.
Diaphragmatic pacing aids breathing but doesn't alter ANS function, often requiring cardiac pacemakers for bradycardia.
Co-implantation of multiple electronic devices raises concerns about device-device interaction (DDI).

Observation:

A 17-year-old male with phrenic nerve injury required both a diaphragm pacemaker and a cardiac pacemaker.
Device interrogation revealed significant DDI when the cardiac pacemaker was in unipolar mode.
Switching the cardiac pacemaker to bipolar mode successfully eliminated the observed DDI.

Findings:

Device-device interaction (DDI) occurred between implanted diaphragm and cardiac pacemakers in a pediatric patient.
Unipolar pacing mode of the cardiac pacemaker was associated with DDI.
Bipolar pacing mode effectively prevented DDI, ensuring safe co-implantation.

Implications:

This case highlights the potential for DDI with co-implanted electronic devices in pediatric patients.
Utilizing bipolar mode for cardiac pacemakers can mitigate DDI risks.
Safe co-implantation strategies are crucial for managing complex conditions involving multiple electronic devices.