Related Experiment Video
Updated: Oct 6, 2025

Intravital Microscopy of the Spleen: Quantitative Analysis of Parasite Mobility and Blood Flow
Published on: January 14, 2012
Spontaneous Splenic Rupture in Malaria Patients: Two Case Reports
Ahmed M Alani1, Jouhar J Kolleri1, Ahmad Al Ekeer1
1Clinical Imaging Department, Hamad Medical Corporation, Doha, QAT.
Spontaneous splenic rupture is a rare complication of severe malaria. Early diagnosis and surgical intervention are critical for patient survival in these cases.
Area of Science:
- Infectious Diseases
- Tropical Medicine
- Surgical Pathology
Background:
- Atraumatic splenic rupture is a rare but life-threatening condition.
- Severe malaria can present with non-specific abdominal pain.
- Travel history to endemic areas is a key epidemiological factor.
Observation:
- Two patients presented to the emergency department with abdominal pain.
- Both patients had a history of travel to malaria-endemic regions.
- Diagnosis revealed spontaneous splenic rupture secondary to severe malaria.
Findings:
- Splenic rupture in malaria is a critical, often overlooked, complication.
- Prompt diagnosis requires high clinical suspicion in patients with malaria and abdominal pain.
- Ultrasonography and CT scans are vital for accurate diagnosis.
Implications:
- Clinicians must maintain a high index of suspicion for splenic rupture in malaria patients.
- Early diagnosis and surgical management (splenectomy) improve patient outcomes.
- Awareness of this rare complication is crucial for emergency medicine and infectious disease specialists.
More Related Videos
07:27A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
Published on: May 16, 2013
09:04In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
Published on: June 8, 2017