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Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium
H L Zhang1, M L Wang1, L Z Yi2
1Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Food Chemistry
|January 16, 2022
Abstract:
Dihydromyricetin has shown many bioactivities in cell level. However, dihydromyricetin was found to be highly instable in cell culture medium DMEM. Here, the underlying degradation mechanism was investigated via UPLC-MS/MS analysis. Dihydromyricetin was mainly converted into its dimers and oxidized products. At lower temperature, dihydromyricetin in DMEM showed higher stability. Vitamin C increased the stability of dihydromyricetin in DMEM probably due to its high antioxidant potential.
