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Updated: Oct 6, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Development of a high-throughput differential mobility separation-tandem mass spectrometry (DMS-MS/MS) method for

Shirin Hooshfar1,2, Simone Tchu1, Cassandra Yun1

  • 1Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, United States.

Journal of Mass Spectrometry and Advances in the Clinical Lab
|January 17, 2022
PubMed
Abstract

Keywords:
6-MAM, 6-MonoacetylmorphineAMPH, amphetamines/ecstasyBENZ, benzodiazepinesBUPR, buprenorphineCE, Collision energyCOV, compensation voltageCXP, collision cell exit potentialDAPPI, atmospheric pressure photo ionizationDART, direct analysis in real timeDC, direct currentDESI, desorption electrospray ionizationDMO, DMS offseDMS, differential mobility separationDP, declustering potentialDR, DMS resolution enhancementDT, DMS cell temperatureDifferential mobility separationDrugs of abuseEDDP, 2-ethylidene1,5-dimethyl-3,3-diphenylpyrrolidineEP, entrance potentialFAIMS, field asymmetric waveform ion mobility spectrometryFSI, fiber spray ionizationGC-MS or LC-MS, gas chromatography- or liquid chromatography-mass spectrometryGS1, ion source gas 1GS2, ion source gas 2IMS, ion mobility spectrometry, IS, internal standards, LOD, limit of detection, MD, modifier, MDC, modifier composition, ME, matrix effectsMRM, multiple reaction monitoringMS/MS, tandem mass spectrometryMass spectrometryOPI, opiatesOXY, oxycodone/oxmorphoneQCs, quality controlsSRM, selected reaction monitoringSV, separation voltageUrine drug screeningWT-ESI, wooden-tip electrospray ionization

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