[What's new in endocrinology]
Maria Mavromati1, Sophie Leboulleux1
1Service d'endocrinologie, diabétologie, nutrition et éducation thérapeutique, Hôpitaux universitaires de Genève, 1211 Genève 14.
Revue Medicale Suisse
|January 20, 2022
Abstract:
The management of Graves' orbitopathy, an extraocular manifestation of the disease and the main contributor to morbidity, is the subject of new recommendations, published in 2021. The treatment of low risk differentiated thyroid cancer is simplified, with less surgery and less radioiodine treatment and at lower dose. The management of acromegaly is oriented towards a personalized approach; prognostic factors are more widely used, and the treatment of complications is emphasized.
Insights
New 2021 guidelines simplify differentiated thyroid cancer treatment and personalize acromegaly management. Graves
Area of Science:
- Endocrinology
- Oncology
- Ophthalmology
Background:
- Graves' orbitopathy is a significant cause of morbidity associated with Graves' disease.
- Differentiated thyroid cancer management has evolved, particularly for low-risk cases.
- Acromegaly treatment requires a tailored approach considering prognostic factors and complications.
Purpose of the Study:
- To present new recommendations for managing Graves' orbitopathy.
- To outline a simplified treatment strategy for low-risk differentiated thyroid cancer.
- To describe a personalized management approach for acromegaly.
Main Methods:
- Review of 2021 published recommendations.
- Analysis of treatment strategies for differentiated thyroid cancer.
- Evaluation of personalized approaches and complication management in acromegaly.
Main Results:
- New recommendations for Graves' orbitopathy management are available.
- Treatment for low-risk differentiated thyroid cancer is simplified, involving less surgery and lower-dose radioiodine.
- Acromegaly management is personalized, utilizing prognostic factors and emphasizing complication treatment.
Conclusions:
- Updated guidelines offer improved management for Graves' orbitopathy.
- Simplified treatment protocols enhance care for low-risk differentiated thyroid cancer.
- Personalized strategies and complication management are key in acromegaly treatment.
Related Concept Videos
01:29The Endocrine System
796
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
796
01:10An Overview of the Endocrine System
10.0K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
The endocrine system collaborates...
10.0K
01:45Endocrine Signaling
65.3K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
65.3K
01:16Hormones Regulating Blood Glucose
4.5K
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
In addition to accelerating glucose uptake and utilization, insulin has...
4.5K
00:59Structures of the Endocrine System
8.7K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
8.7K
00:46What is the Endocrine System?
417.3K
The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
417.3K