Related Experiment Video
Updated: Sep 11, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Primary hyperaldosteronism : updates]
Imene Achek Bouajila1, Maria Mavromati2, Belén Ponte1
1Service de néphrologie et hypertension, Hôpitaux universitaires de Genève, 1211 Genève 14.
Abstract:
Primary hyperaldosteronism is a common and potentially curable cause of hypertension (HTN), affecting 10 to 15% of hypertensive patients. Underdiagnosed, it is associated with a higher cardiovascular risk than essential HTN. Recent recommendations from the Endocrine Society (2025) and the European Society of Cardiology (2024) advocate screening in all patients with newly diagnosed HTN. The diagnosis is based on an increased aldosterone-to-renin ratio. A new classification helps assess disease severity and the likelihood of a unilateral form,. Treatment relies on mineralocorticoid receptor antagonists or surgery in cases of lateralized disease, according to patient preference. New therapies targeting aldosterone synthase are currently under development.
Related Concept Videos
Antihypertensive Drugs: Potassium-Sparing Diuretics
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Hormonal Regulation
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Direct Renin Inhibitors
Antihypertensive Drugs: Angiotensin II Receptor Blockers
