Synthesis, Characterization and Biomedical Application of Silver Nanoparticles
Ashwini Naganthran1, Gayathiri Verasoundarapandian1, Farah Eryssa Khalid1
1Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Materials (Basel, Switzerland)
|January 21, 2022
Summary
Silver nanoparticles (AgNPs) show potent antibacterial, antiviral, and antifungal properties. This review analyzes synthesis methods and biomedical applications, highlighting AgNPs as effective solutions for wound healing and bone regeneration.
Area of Science:
- Biotechnology
- Nanomaterials Science
- Biomedical Engineering
Background:
- Silver nanoparticles (AgNPs) exhibit significant antibacterial, antiviral, and antifungal activities.
- AgNPs are synthesized via chemical, physical, and biological methods, each with distinct advantages and limitations.
- The biomedical sector increasingly utilizes AgNPs for their therapeutic potential.
Purpose of the Study:
- To conduct a bibliometric analysis of literature trends in AgNP synthesis methods from 2010-2020.
- To explore the author keywords related to the biomedical applications of biosynthesized AgNPs.
- To review the synthesis, characterization, and diverse biomedical applications of AgNPs.
Main Methods:
- Bibliometric analysis of 10,278 publications from the Scopus database (2010-2020) using Microsoft Excel.
- Bibliometric clustering and mapping software to analyze author keywords from 224 documents on biosynthesized AgNPs.
- Literature review of AgNP synthesis, characterization, and biomedical applications.
Main Results:
- Analysis of publication trends revealed significant research activity in AgNP synthesis and applications.
- Key biomedical applications identified include antibacterial, antiviral, anticancer, bone healing, dental applications, and wound healing.
- Biosynthesized AgNPs are a focal point for research into novel therapeutic strategies.
Conclusions:
- AgNPs offer a versatile and effective solution for various biomedical challenges.
- Understanding synthesis methods and characterization is crucial for optimizing AgNP applications.
- Continued research into AgNPs promises advancements in treating infections, promoting tissue regeneration, and developing new therapies.
