Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Mutations00:36

Viral Mutations

34.4K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
34.4K
Introduction to Virus01:28

Introduction to Virus

336
Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
336
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

16.6K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
16.6K
Viral Recombination00:57

Viral Recombination

23.9K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.9K
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

190
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
190
Viral Structure00:56

Viral Structure

65.9K
Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
65.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Covid-19 vaccine tweak could better tackle today's variants.

New scientist (1971)·2023
Same author

Coronavirus mutations offer a new insight into evolution.

New scientist (1971)·2023
Same author

The next covid-19 vaccines.

New scientist (1971)·2023
Same author

Monkeypox unnoticed?

New scientist (1971)·2022
Same author

Mutation-inducing drugs could raise virus dangers.

New scientist (1971)·2022
Same author

Could vaccines end the pandemic?

New scientist (1971)·2022

Related Experiment Video

Updated: Oct 5, 2025

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
06:08

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

1.4K

Understanding omicron.

Michael Le Page

    New Scientist (1971)
    |January 24, 2022
    PubMed
    Summary
    This summary is machine-generated.

    Researchers are uncovering why the Omicron variant of the coronavirus differs significantly from previous strains. These studies explore the unique characteristics driving Omicron

    More Related Videos

    Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
    09:26

    Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

    Published on: June 30, 2023

    1.3K
    Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
    09:02

    Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

    Published on: September 22, 2023

    1.6K

    Related Experiment Videos

    Last Updated: Oct 5, 2025

    Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
    06:08

    Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

    Published on: September 8, 2023

    1.4K
    Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
    09:26

    Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

    Published on: June 30, 2023

    1.3K
    Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
    09:02

    Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

    Published on: September 22, 2023

    1.6K

    Area of Science:

    • Virology
    • Infectious Diseases
    • Genomics

    Background:

    • The emergence of SARS-CoV-2 variants, such as Omicron, has presented unique public health challenges.
    • Understanding the molecular and epidemiological differences between variants is crucial for effective pandemic response.

    Purpose of the Study:

    • To investigate the specific biological and genetic factors contributing to the distinct behavior of the Omicron variant.
    • To compare Omicron's characteristics with those of preceding SARS-CoV-2 variants.

    Main Methods:

    • Analysis of genomic sequencing data to identify mutations unique to Omicron.
    • Comparative studies on viral replication, transmissibility, and immune evasion.

    Main Results:

    • Omicron exhibits a distinct mutation profile in its spike protein compared to Delta and other variants.
    • Early findings suggest differences in cellular entry mechanisms and immune system interaction.

    Conclusions:

    • The unique properties of Omicron are likely due to a combination of specific genetic mutations.
    • Further research is ongoing to fully elucidate Omicron's distinct epidemiological and clinical behavior.