Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

498
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
498
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

5.5K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
5.5K
Autoimmune Disorders01:29

Autoimmune Disorders

756
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
756
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

74
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
74
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

80
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
80
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

931
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
931

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cohort profile: Swiss personalized health network cohort consortium.

European journal of epidemiology·2026
Same author

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis.

International journal of dermatology·2026
Same author

[Cardiac sarcoidosis in 2026 : current perspectives].

Revue medicale suisse·2026
Same author

Long-term citrate treatment in high-risk kidney stone formers is not associated with metabolic adverse effects.

Clinical kidney journal·2026
Same author

Destructive Mold Osteomyelitis of the Wrist Caused by <i>Scedosporium apiospermum</i>-A Case Report.

Journal of clinical medicine·2026
Same author

Purpura and Anasarca in a Kidney-Transplanted Recipient: A Quiz.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Metamizole-induced agranulocytosis: utilisation trends, pharmacovigilance signals and regulatory risk-minimisation in Switzerland.

Swiss medical weekly·2026
Same journal

Female genital mutilation/cutting and risk of obstetric anal sphincter injury at delivery.

Swiss medical weekly·2026
Same journal

Drug prescription before and after implementation of a CPOE system on the Paediatric Intensive Care Unit: a quality improvement study.

Swiss medical weekly·2026
Same journal

Trends in health- and lifestyle-related aspects in women of childbearing age: analysis of Swiss Health Survey data between 1992 and 2022.

Swiss medical weekly·2026
Same journal

Microplastics in the air and potential health risks - a narrative review.

Swiss medical weekly·2026
Same journal

Potentially inappropriate medication: prevalence, risk of hospitalisation and associated healthcare costs in the general older population of Switzerland.

Swiss medical weekly·2026
See all related articles

Related Experiment Video

Updated: Oct 5, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.3K

Sarcoidosis - a multisystem disease.

Daniel P Franzen1, Martin Brutsche2, Jakob Nilsson3

  • 1Department of Pulmonology, University Hospital Zurich, Switzerland.

Swiss Medical Weekly
|January 24, 2022
PubMed
Summary
This summary is machine-generated.

Sarcoidosis is an inflammatory disease causing granulomas. Treatment varies by organ involvement, including immunosuppressants and biologics, with a focus on multidisciplinary care for diverse patient needs.

More Related Videos

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
10:21

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

562
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.7K

Related Experiment Videos

Last Updated: Oct 5, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.3K
Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
10:21

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

562
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.7K

Area of Science:

  • Immunology
  • Rheumatology
  • Pulmonology

Background:

  • Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation.
  • It involves diverse organ systems, leading to varied clinical presentations.
  • Immune system activation, including innate and adaptive responses, is central to its pathology.

Purpose of the Study:

  • To provide a comprehensive overview of sarcoidosis.
  • To discuss the diverse clinical manifestations and diagnostic approaches.
  • To outline current and emerging treatment strategies for sarcoidosis.

Main Methods:

  • Literature review of sarcoidosis pathogenesis, clinical features, and treatment.
  • Analysis of current therapeutic guidelines and emerging therapies.
  • Emphasis on multidisciplinary approach and patient-centered care.

Main Results:

  • Sarcoidosis affects multiple organs, with lungs, lymph nodes, skin, and eyes most common.
  • Treatment ranges from topical therapies to systemic immunosuppressants (glucocorticoids, methotrexate) and biologics (TNF-alpha inhibitors).
  • Para-sarcoidosis symptoms like fatigue require specific management, potentially including rehabilitation.

Conclusions:

  • Sarcoidosis management requires a tailored, multidisciplinary approach based on organ involvement and patient factors.
  • Further research, including real-world data, is needed to understand endotypes and optimize treatment pathways.
  • Addressing all manifestations, including para-sarcoidosis symptoms, is crucial for improving patient quality of life.