ST Segment Elevation Myocardial Infarction in the COVID-19 Era: Appraisal of the Evidence
Somto Nwaedozie1, Shereif H Rezkalla2,3
1Department of Internal Medicine, Marshfield Clinic, Marshfield, Wisconsin USA nwaedozie.somto@marshfieldclinic.org.
Insights
COVID-19 significantly impacts ST-elevation myocardial infarction (STEMI) management and outcomes. Delays in treatment, particularly primary percutaneous coronary intervention (PCI), increase risks like no reflow and worsen patient prognosis.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has complicated the care of ST-elevation myocardial infarction (STEMI) patients.
- Patients with cardiovascular risk factors and COVID-19 face increased STEMI risk.
Observation:
- Global trends show delayed STEMI management, leading to poorer clinical outcomes.
- Prolonged intervention times correlate with a higher incidence of no reflow, a negative prognostic factor.
Findings:
- Timely primary percutaneous coronary intervention (PCI) is crucial for STEMI management, ideally within 90 minutes of hospital arrival.
- A coordinated, algorithmic approach across healthcare services is essential for optimal STEMI patient outcomes during the pandemic.
Implications:
- This case report underscores the challenges in performing PCI for STEMI in the COVID-19 era.
- Standardized protocols are vital to mitigate adverse outcomes and ensure effective STEMI care amidst public health crises.
Abstract:
The COVID-19 pandemic continues to present a public health challenge and has had a significant impact on the presentation, time-dependent management, and clinical outcomes of ST elevation myocardial infarction (STEMI). Patients with COVID-19 and pre-disposing cardiovascular risk factors like hypertension, hyperlipidemia, and diabetes mellitus are at a higher risk of developing STEMI, and global trends have highlighted delayed management of STEMI, which may contribute to worse clinical outcomes. Prolonged time to intervention has also resulted in an increased rate of no reflow, which is an independent risk factor for worse outcomes in these patients. Timely primary percutaneous coronary intervention (PCI) remains standard of care for STEMI and can be attained within the recommended 90 minutes timeline from hospital presentation. A coordinated, safe, standardized, algorithmic approach among emergency medical services, emergency departments, and cardiac catheterization laboratory is needed to ensure optimal patient outcome during and after the COVID-19 pandemic. The focus of this case report is to highlight the challenges of PCI for ST elevation myocardial infarction in the COVID-19 era.
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