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Postextubation fluid balance is associated with extubation failure: a cohort study
Priscila Albrecht Dos Santos1, Alexandre Ribas1, Thiele Cabral Coelho Quadros1
1Departamento de Terapia Intensiva, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul - Porto Alegre (RS), Brasil.
Revista Brasileira De Terapia Intensiva
|February 2, 2022
Summary
A negative fluid balance after mechanical ventilation is linked to extubation failure. Maintaining a neutral or positive fluid balance may improve patient outcomes post-extubation.
Area of Science:
- Critical Care Medicine
- Pulmonary Medicine
- Fluid Management
Background:
- Extubation failure is a significant complication following mechanical ventilation.
- Optimizing fluid balance is crucial for patient recovery in intensive care units.
Purpose of the Study:
- To investigate the association between 48-hour postextubation fluid balance and the incidence of extubation failure.
- To identify fluid balance parameters that predict extubation outcomes.
Main Methods:
- Prospective cohort study in a tertiary hospital ICU.
- Included 101 patients requiring mechanical ventilation for ≥24 hours.
- Assessed extubation failure (reintubation within 72 hours) and a combined outcome.
Main Results:
- 28.7% of patients experienced extubation failure.
- A negative fluid balance >1L in 48 hours postextubation was associated with lower failure rates (12.0% vs 34.2%).
- Negative fluid balance <1L and ventilation duration were independent predictors of extubation failure.
Conclusions:
- Postextubation fluid balance is a significant predictor of extubation failure.
- Further research is needed to determine if managing fluid balance can improve weaning outcomes.
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