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Summarising the precision statistics from collaborative trials.
Analytical Methods : Advancing Methods and Applications
|February 2, 2022
Summary
Collaborative trials offer reliable analytical procedure validation by estimating reproducibility standard deviations. However, their high cost is limiting their use despite increasing demand for this crucial data.
Area of Science:
- Analytical Chemistry
- Method Validation
Background:
- Collaborative trials are considered the gold standard for validating analytical procedures.
- The primary output is reproducibility standard deviations, essential for estimating measurement uncertainty.
Purpose of the Study:
- To highlight the value of collaborative trials in analytical science.
- To address the declining popularity of these trials due to cost.
Main Methods:
- The study discusses the established methodology of interlaboratory collaborative trials.
- Focuses on the collection and interpretation of reproducibility standard deviations.
Main Results:
- Reproducibility standard deviations from trials accurately estimate uncertainties in proficient laboratories.
- Collaborative trials are costly, ranging from £50k-£100k per trial.
Conclusions:
- Despite their reliability, the high expense of collaborative trials is a significant drawback.
- There is a growing need for the data generated by these trials, creating a conflict.
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