[Development and differentiation of bone marrow mechanocytes]

Morphological studies in the model with the complete destruction of bone marrow in the diaphysis of the tubular bone have revealed the process of stromal elements regeneration. Within the first 24 hours after the trauma insignificant accumulations of fibroblast-like cells in the lumen of some vascular channels have been observed in cell-free cortical plates. In two days spheric cells with a large dense nucleus were detected in tissue-free bone-marrow diaphysis cavity. This fact seems indicative of the viability of the vascular channel cells. This was manifested in the regained tinctorial and biological properties (i.e. the ability to proliferate). The recovery of these properties are likely to be related to vessel pericytes in the microcirculatory net of the vascular channels.