Related Experiment Video
Updated: Oct 4, 2025
03:23
Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
966
Plasma membrane lesion type total intestinal eosinophilic enteritis: a case report
Yu-Jing He1, Jin-Yu Sun1, Pan Wang2
1Department of Gastroenterology, The 940th Hospital of Joint Service Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, Gansu, China; The First Clinical Medical College, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, Gansu, China.
Transplant Immunology
|February 5, 2022
Summary
Eosinophilic gastroenteritis, a rare condition, involves eosinophil buildup in the gut. This case highlights a rare plasma membrane lesion-type total intestinal eosinophilic enteritis successfully treated with prednisone.
Area of Science:
- Gastroenterology
- Immunology
- Pathology
Background:
- Eosinophilic gastroenteritis is a rare gastrointestinal disorder characterized by eosinophil infiltration in the GI tract and elevated peripheral blood eosinophils.
- This report details a unique case of plasma membrane lesion-type total intestinal eosinophilic enteritis.
Observation:
- A 20-year-old male presented with 15 days of abdominal distension and ascites.
- Diagnostic workup including intestinal biopsy, ascites examination, blood counts, and bone marrow puncture revealed extensive eosinophil infiltration throughout the duodenum, small intestine, and colon.
Findings:
- The patient was diagnosed with plasma membrane lesion-type total intestinal eosinophilic enteritis.
- Treatment with prednisone for four weeks resulted in complete symptom resolution.
- Endoscopic follow-up showed a smooth intestinal mucosa, indicating successful treatment.
Implications:
- Clinicians should consider eosinophilic enteritis in patients with unexplained abdominal distension and ascites.
- Gastrointestinal endoscopy, biopsy, and peripheral blood eosinophil counts are crucial for diagnosis.
- Prompt diagnosis and treatment with corticosteroids can lead to favorable outcomes in this rare condition.
