Case of reversible Mobitz type II atrioventricular block after the use of injectable antipsychotics

Area of Science:

• Cardiology
• Pharmacology
• Psychiatry

Background:

• Mobitz type II atrioventricular block is generally considered a consequence of irreversible His-Purkinje system disease.
• Reversible causes of atrioventricular block are less commonly recognized but clinically significant.

Observation:

• A 75-year-old patient diagnosed with schizophrenia presented with Mobitz type II atrioventricular block.
• The patient was undergoing treatment with antipsychotic medication.

Findings:

• A rare association was identified between the patient's Mobitz type II atrioventricular block and the use of antipsychotic medication.
• This suggests a potential reversible etiology for the atrioventricular block, contrary to its typical permanent nature.

Implications:

• Clinicians should consider medication-induced cardiac side effects, including antipsychotics, when evaluating Mobitz type II atrioventricular block.
• Identifying reversible factors can lead to improved patient management and potentially avoid unnecessary invasive procedures.