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THE DYNAMICS OF LIPID METABOLISM IN PATIENTS WITH MORBID OBESITY DEPENDING ON THE TYPE OF PERFORMED SURGERY
E Smetanin1, K Outlev1, E Kruchinin1
1Tyumen State Medical University, Russia.
Abstract:
The objective of the study - to determine changes in the lipidogram (total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol) as a component of the metabolic syndrome in patients suffering from morbid obesity after bariatric surgery (biliopancreatic bypass surgery, laparoscopic gastric banding, laparoscopic longitudinal gastric resection). The study was based on 166 clinical cases. To achieve this goal, patients were divided into three groups according to the type of surgery underground. All patients in the preoperative period were obese with BMI ranging from 45 to 54.9 and had severe abnormalities in the parameters of the lipidogram (total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol). After surgical treatment of patients with morbid obesity, depending on the type of surgical aid, data on the normalization of lipidogram parameters were obtained, but these changes had different dynamics of changes. Thus, atherogenic lipid fractions significantly decreased in all patients, irrespective of the type of surgery. The decrease of total cholesterol was higher in patients who underwent biliopancreatic diversion. Total cholesterol decreased significantly in patients who underwent biliopancreatic bypass surgery. Thus, bariatric surgeries analyzed in the study lead to normalization of the lipid spectrum as a component of the metabolic syndrome in patients with morbid obesity.
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