CLINICAL AND HAEMATOLOGICAL CHANGES AMONG HIV PATIENTS

Area of Science:

• Hematology
• Infectious Diseases
• Oral Medicine

Background:

• Anemia of chronic diseases (ACD) is a concern in HIV patients.
• Highly active antiretroviral therapy (ART) may impact red blood cell parameters.
• Oral health changes can be linked to systemic conditions in HIV.

Purpose of the Study:

• To investigate red blood cell changes in HIV-infected individuals.
• To explore the characteristics of ACD in HIV patients.
• To establish connections between oral cavity changes and peripheral blood parameters in HIV.

Main Methods:

• Analysis of red blood cell indicators in HIV patients.
• Assessment of patients based on ART status.
• Evaluation of red blood cell parameters relative to CD4+ lymphocyte counts and disease stage.
• Correlation of blood parameters with periodontal tissue status.

Main Results:

• Significant red blood cell count alterations were observed in HIV patients, irrespective of ART use.
• Clinical signs of anemia were identified in the maxillofacial area and oral cavity.
• A relationship was found between oral cavity changes and peripheral blood parameters.

Conclusions:

• HIV infection and ART influence red blood cell parameters, contributing to anemia.
• Oral health status is associated with anemia of chronic diseases in HIV patients.
• Further research is needed to elucidate the pathogenetic links between periodontal disease and ACD in HIV.