Gender-affirming Mastectomy with Concurrent Oncologic Mastectomy.

Area of Science:

• Oncology
• Plastic Surgery
• Gender-Affirming Care

Background:

• Transmasculine individuals may retain natal breast tissue without prior gender-affirming mastectomy.
• Breast cancer diagnosis in this population necessitates oncologic treatment.
• Concurrent oncologic mastectomy and gender-affirming reconstruction is a novel approach.

Purpose of the Study:

• To report the first series of simultaneous oncologic mastectomy and gender-affirming reconstruction.
• To evaluate the safety and outcomes of this combined surgical approach.

Main Methods:

• Retrospective chart review of patients undergoing gender-affirming mastectomy from February 2017 to October 2021.
• Inclusion criteria: preoperative breast cancer diagnosis or pathologic lesions.
• Data collected: demographics, comorbidities, surgical details, oncologic history; multidisciplinary surgical teams involved.

Main Results:

• Five patients with breast pathologies undergoing gender-affirming mastectomy were identified.
• Average age was 50.2 years; no patients were on testosterone therapy.
• One patient had a positive sentinel lymph node requiring adjuvant therapy; no oncologic recurrence observed during follow-up (mean 20.6 months).

Conclusions:

• Simultaneous oncologic mastectomy and gender-affirming reconstruction can be safely performed.
• A multidisciplinary approach involving plastic and breast surgeons is crucial.
• This combined procedure offers oncologic safety and aesthetic gender-affirming outcomes.