Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular Engineering of Vibronic Coupling Enables High-Temperature Solar-Thermal Conversion in an Organic Material.

Angewandte Chemie (International ed. in English)·2026

Same author

Water in Triple-Bond-Based Polymerizations: Roles as a Solvent or Monomer.

Polymer science & technology (Washington, D.C.)·2026

Same author

Ultra-Stable 2D Magneto-Fluorescent Probe-Mediated Multiplex Immunochromatographic Assay for Precise Bedside Detection of Sepsis.

ACS nano·2026

Same author

Spontaneous Thiol-Yne Click Polymerization of Aliphatic Thiols and Sulfonyl-Activated Alkynes: A Facile Route to Z-Stereoregular Poly(β-thiolvinylsulfone)s.

Macromolecular rapid communications·2026

Same author

Covalent Protein-Conjugated Photosensitizer Efficiently Evokes Immunogenic Cell Death for Cancer Vaccine Preparation.

Journal of medicinal chemistry·2026

Same author

Acid-induced "turn-on" fluorescence of β-aminoacrylate-based molecules and polymers toward anti-counterfeiting applications.

Chemical communications (Cambridge, England)·2026

Same journal

Metal-Ion-Modulated Stabilization of Intermediates in Diphenylalanine and Phenylalanine Self-Assembly: Roles of Metal-Ion-Specific Salt Bridges and Hydrophobic Interactions.

Biomacromolecules·2026

Same journal

Understanding Processing-Structure-Property Relationships in Spun Spidroin-Mimetic Fibers Using Molecular Dynamics Simulation.

Biomacromolecules·2026

Same journal

Exploring the Antibacterial Potential of Bis-MPA Dendrimers Bearing Cu(II) and Zn(II) Complexes.

Biomacromolecules·2026

Same journal

Toward Sustainable Optics: Fully Biomass-Based Vitrimer Film for Near-Infrared Transparency.

Biomacromolecules·2026

Same journal

Poly(furfuryl alcohol) as a Surface Modifier for Cellulose Nanocrystals Reinforced HDPE Nanocomposites.

Biomacromolecules·2026

Same journal

Cutinase Adsorption to Polyester Surfaces Modulates Dissolved Oligomer Speciation during Enzymatic Depolymerization.

Biomacromolecules·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 3, 2025

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Published on: September 12, 2019

Aggregation-Induced Emission-Active Biomacromolecules: Progress, Challenges, and Opportunities.

Rong Hu^1,2, Jia Wang¹, Anjun Qin¹

¹State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, AIE Institute, Center for Aggregation-Induced Emission, South China University of Technology, 510641 Guangzhou, China.

Biomacromolecules

|February 16, 2022

Summary

This summary is machine-generated.

Aggregation-induced-emission (AIE) biomacromolecules exhibit unique properties for biomedical uses. This perspective reviews AIE biomacromolecule development, applications, and future research directions.

More Related Videos

4D Imaging of Protein Aggregation in Live Cells

4D Imaging of Protein Aggregation in Live Cells

Published on: April 5, 2013

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans

Published on: December 17, 2021

Related Experiment Videos

Last Updated: Oct 3, 2025

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Published on: September 12, 2019

4D Imaging of Protein Aggregation in Live Cells

4D Imaging of Protein Aggregation in Live Cells

Published on: April 5, 2013

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans

Published on: December 17, 2021

Area of Science:

Biomaterials Science
Organic Chemistry
Nanotechnology

Background:

Aggregation-induced-emission (AIE) phenomena offer unique photophysical properties.
AIE-active biomacromolecules display distinct characteristics in aggregated states compared to molecular states.
These properties unlock novel possibilities for advanced biomedical applications.

Purpose of the Study:

To provide a comprehensive overview of the development of AIE-active biomacromolecules.
To highlight significant advancements in synthesis, structure-property relationships, and applications.
To discuss current challenges and future opportunities in the field.

Main Methods:

Review of synthetic strategies for AIE-active biomacromolecules.
Analysis of structure-property correlations in AIE biomaterials.
Exploration of diverse biomedical applications.

Main Results:

Significant progress has been achieved in the preparation and characterization of AIE-active biomacromolecules.
Established structure-property relationships guide the design of novel AIE biomaterials.
Demonstrated potential in various biomedical fields, including imaging and diagnostics.

Conclusions:

AIE-active biomacromolecules represent a rapidly advancing area with transformative potential.
Further research into synthesis, characterization, and application is crucial.
This field offers exciting opportunities for innovation in biomaterials and aggregate science.