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Ptf1a Promoter-Driven Cre Expression During Spermatogenesis Causes Germline Recombination

Jiale Wang1, Oliver Wang1, Yan Bi2

  • 1From the Department of Cancer Biology.

Pancreas
|February 23, 2022
PubMed
Summary

Ptf1a-Cre mouse lines are crucial for pancreatic research. The Ptf1a-Cre Cvw line, like the Hnak line, exhibits paternal germline recombination due to Cre expression during spermatogenesis.

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