Factors associated with febrile seizures among children

Febrile seizures are usually benign and are not presented with neurological manifestation. However, complex febrile seizures are presented with recurrence and might require meticulous management. The aim of this study was to evaluate the demographic, clinical, and laboratory parameters of children with febrile seizures and the correlation between these factors.

In this retrospective study, children presented with febrile seizure in 2019 presented (XXX) were included. Data based on their history, physical examination, and laboratory tests and discharge recommendations were recorded in a checklist. Data were computerized and statistically analyzed using SPSSv25.

Of 77 patients were studied, the mean age of the patients was 29.4 ± 17.6. The mean duration of seizures was 5.09 ± 3.78 min and the mean temperature during seizures was 38.41 ± 0.83 °C. In 44 (57.14%) patients no cause of the fever was recorded. 10 (12.99%) patients had multiple seizures within 24 h 70 (90.91%) seizures ended without medication, and 5 (6.49%) patients were treated with diazepam. The gender of the patients was only correlated with white blood cells, p = 0.014. Other laboratory parameters did not show significant correlation with the gender, p > 0.05. The discharge recommendation was significantly correlated with recurrence within 24 h and type of seizure, p < 0.001, respectively. Lab parameters were significantly associated with family history, p = 0.036 and post-seizure drug, p = 0.005.

Our study showed that biochemical findings may not be suggestive of febrile seizures and recurrence of seizures and family history is associated with the course of treatment in terms of drugs and imaging.