Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

6.8K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
6.8K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

76
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
76
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.6K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probabilistic Safe Zone Mapping for S1 Screw Placement Using 1000 Lumbosacral CT Scans: A Study Protocol for a Bilateral, Two-Rater, Multi-Offset Anatomical Modeling Study.

Journal of clinical medicine·2026
Same author

Comparing image quality of synchrotron and laboratory nano-CT scans: a round robin study.

Journal of synchrotron radiation·2026
Same author

Synchrotron-Based Analysis of Conical Implant-Abutment Connections Under Mechanical Load: How Embedding Materials Influence the Microgap and Implant Shoulder Deformation.

Clinical and experimental dental research·2025
Same author

Determining the optimal choice of attenuation filters and propagation distance for polychromatic phase-contrast micro-computed tomography of a multi-material electromotor using synchrotron radiation.

Journal of synchrotron radiation·2025
Same author

In vitro assessment of internal implant-abutment connections with different cone angles under static loading using synchrotron-based radiation.

BMC oral health·2024
Same author

Development of an Algorithm for Correct Placement of the Basal Electrode Contact in the Context of Anatomy-Based Cochlear Implantation: A Proof of Concept.

Audiology & neuro-otology·2024

Related Experiment Video

Updated: Oct 2, 2025

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects
10:16

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects

Published on: February 8, 2014

12.4K

Robust Image Reconstruction Strategy for Multiscalar Holotomography.

Maximilian Ullherr1, Matthias Diez1, Simon Zabler1

  • 1Lehrstuhl für Röntgenmikroskopie, Universität Würzburg, Josef-Martin-Weg 63, 97074 Würzburg, Germany.

Journal of Imaging
|February 24, 2022
PubMed
Summary

Holotomography offers high-contrast imaging for low X-ray absorption samples. Multiscalar holotomography addresses field of view limitations and reconstruction challenges in region of interest computed tomography (ROI CT).

Keywords:
CTROIX-raycomputed tomographyholotomographymultiscalar holotomographyreconstructionregion of interest

More Related Videos

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
08:41

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

11.7K
Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
09:56

Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales

Published on: August 21, 2019

7.0K

Related Experiment Videos

Last Updated: Oct 2, 2025

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects
10:16

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects

Published on: February 8, 2014

12.4K
Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
08:41

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

11.7K
Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
09:56

Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales

Published on: August 21, 2019

7.0K

Area of Science:

  • X-ray imaging
  • Computed Tomography
  • Phase Contrast Imaging

Background:

  • Holotomography enhances contrast for low X-ray absorption samples.
  • High optical resolution limits the field of view (FOV) in holotomography.
  • Local tomography (region of interest computed tomography or ROI CT) faces filter problems in reconstruction and phase retrieval.

Purpose of the Study:

  • Investigate the impact of filter problems in ROI CT.
  • Discuss approximate solutions for these filter problems.
  • Evaluate multiscalar holotomography to overcome FOV limitations and reconstruction issues.

Main Methods:

  • Analyzing filter problems in holotomography reconstruction.
  • Developing and applying multiscalar holotomography.
  • Combining ROI CT with lower-resolution non-ROI CT measurements.

Main Results:

  • Filter problems significantly impact CT reconstruction and phase retrieval in ROI CT.
  • Multiscalar holotomography effectively mitigates filter problems.
  • Reconstruction of larger sample areas is achieved with a trade-off in resolution for non-ROI areas.

Conclusions:

  • Multiscalar holotomography provides a viable solution for imaging large, low-absorption samples.
  • This technique balances the need for high-resolution ROI imaging with broader sample coverage.
  • Further investigation into optimizing resolution trade-offs is warranted.