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Kingella kingae and Viral Infections
Romain Basmaci1,2, Philippe Bidet2,3, Stéphane Bonacorsi2,3
1Service de Pédiatrie-Urgences, Hôpital Louis-Mourier, APHP, F-92700 Colombes, France.
Viral infections may promote Kingella kingae infections in young children. This review explores the link between Kingella kingae and common viral illnesses, suggesting further research is needed.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Kingella kingae is a common cause of bone and joint infections in toddlers.
- The oropharynx serves as the reservoir and entry point for K. kingae.
- Viral infections are hypothesized to facilitate K. kingae infections.
Purpose of the Study:
- To review the current understanding of the relationship between K. kingae and viral infections.
- To explore evidence supporting the hypothesis that viral infections precede or coincide with K. kingae infections.
Main Methods:
- Narrative review of existing literature.
- Analysis of case reports and epidemiological data.
- Identification of common viral pathogens associated with K. kingae infections.
Main Results:
- Viral symptoms frequently co-occur with K. kingae infections.
- Specific viral syndromes like hand, foot, and mouth disease are linked to K. kingae.
- Human rhinovirus and coxsackievirus are frequently identified during K. kingae infections.
- Temporal association observed between human rhinovirus circulation and K. kingae outbreaks.
Conclusions:
- A strong association exists between viral infections and K. kingae infections in children.
- Viruses, particularly from the Picornaviridae family, may play a role in K. kingae pathophysiology.
- Further molecular studies are required to elucidate the exact mechanisms involved.
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