Related Experiment Video
Updated: Oct 2, 2025
10:28
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
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Gastric carcinoma's primary presentation as multiple cutaneous nodules throughout the body
Amir A Bajoghli1, Alexandra Piselli2, Helen Kemprecos3
1Skin and Laser Surgery Center, PC 1359 Beverly Rd 2nd Floor, McLean, VA 22101 United States.
Cancer Treatment and Research Communications
|February 26, 2022
Summary
Cutaneous metastasis from stomach cancer is rare but signals advanced disease. Early recognition and treatment, like chemotherapy, can lead to long-term patient response.
Area of Science:
- Oncology
- Dermatology
Background:
- Cutaneous metastasis from internal malignancies is uncommon.
- Prompt diagnosis of skin metastases indicates advanced disease and poor prognosis.
Observation:
- A 44-year-old man presented with multiple facial, truncal, and extremity nodules.
- Skin biopsy showed poorly differentiated metastatic carcinoma.
- Esophagogastroduodenoscopy revealed invasive signet-ring adenocarcinoma of the stomach.
Findings:
- The patient had widespread skin and bone metastases from gastric adenocarcinoma.
- Treatment involved an oxaliplatin-based chemotherapy regimen and denosumab for bone metastases.
Implications:
- This case highlights the importance of considering cutaneous metastases in unexplained skin lesions.
- Effective management with chemotherapy and targeted agents can achieve durable disease control.
- Gastric adenocarcinoma can present with unusual metastatic patterns, necessitating a high index of suspicion.
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