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Related Experiment Videos

Democratizing data at Novartis through clinical trial data access.

Gabriel S Eichler1, Georges Imbert1, Janice Branson1

  • 1Novartis AG, Basel, Switzerland.

Drug Discovery Today
|March 1, 2022
PubMed
Summary

Novartis streamlined clinical trial data access through the data42 program, enabling faster research and development (R&D) by automating most internal data requests. This risk-based approach overcame previous technical and policy barriers.

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Area of Science:

  • Biopharmaceutical data management
  • Clinical trial data accessibility
  • Health informatics

Background:

  • Biopharmaceutical companies face challenges in accessing and utilizing clinical trial data due to technical, cultural, and policy barriers.
  • Limited data accessibility hinders research and development (R&D) efficiency and innovation.

Purpose of the Study:

  • To describe Novartis's data42 program, designed to overcome hurdles in clinical trial data access.
  • To explore the formulation of a risk-based data access approach involving diverse stakeholders.
  • To assess the impact of streamlined data access on R&D activities within Novartis.

Main Methods:

  • Implementation of the data42 program at Novartis.
  • Development of a risk-based framework for anonymized clinical trial data access.
Keywords:
Clinical trialsData DemocratizationData accessData lakeDigital transformation

Related Experiment Videos

  • Engagement of enterprise-wide stakeholders in defining data access policies.

    • Main Results:

    • Most internal clinical trial data requests are now automatically approved.
    • Significant improvement in the utilization of anonymized clinical trial data by R&D associates.
    • Successful mitigation of technical, cultural, and policy impediments to data access.

    Conclusions:

    • The data42 program demonstrates a successful model for enhancing clinical trial data accessibility and use within biopharmaceutical companies.
    • A risk-based, stakeholder-driven approach can effectively streamline data access and accelerate R&D.
    • The Novartis experience offers valuable insights for the broader biopharmaceutical industry seeking to improve data management and utilization.