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Published on: February 26, 2013
Effects of Supervised Exercise Training on Atrial Fibrillation: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.
Adam Oesterle1, Shaun Giancaterino, Megan G Van Noord
1Department of Cardiology, University of California, San Francisco-Veterans Affairs Medical Center, San Francisco (Drs Oesterle and Pellegrini); Department of Cardiology, University of California, Davis (Drs Giancaterino, Fan, Srivatsa and Amsterdam); and University of California, Davis (Ms Van Noord).
Supervised exercise training safely reduces atrial fibrillation (AF) recurrence and improves quality of life and cardiorespiratory fitness in patients. Further research is needed to fully understand exercise effects on AF burden.
Area of Science:
- Cardiology
- Exercise Physiology
Background:
- Atrial fibrillation (AF) is linked to sedentary lifestyles and even seen in endurance athletes.
- The therapeutic role of exercise in managing AF remains unclear.
Purpose of the Study:
- To investigate the impact of supervised exercise on atrial fibrillation outcomes.
- To evaluate exercise's effect on AF recurrence, burden, symptoms, quality of life, and cardiorespiratory fitness.
Main Methods:
- A meta-analysis of 13 randomized controlled trials (RCTs) involving 1155 participants with AF.
- Primary outcome: AF recurrence and burden. Secondary outcomes: AF symptoms, quality of life, and cardiorespiratory fitness (CRF).
- Included diverse exercise types: cardiac rehabilitation, aerobic training, Qi Gong, interval training, and yoga.
Main Results:
- Exercise training significantly reduced AF recurrence (RR = 0.77).
- Quality of life and CRF showed significant improvements (SMD = 0.56 for CRF).
- AF burden reduction was observed only with continuous monitoring; no difference in adverse events.
Conclusions:
- Supervised exercise is a safe intervention for AF patients.
- Exercise training effectively lowers AF recurrence and enhances quality of life and CRF.
- Further large RCTs are necessary to clarify exercise's impact on AF burden and symptoms.
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