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Cell-based biocomposite engineering directed by polymers.

Wenshuo Wang^1,2, Shutao Wang^3,4

¹Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.

|March 4, 2022

Summary

This summary is machine-generated.

Researchers are using polymers to engineer cells into advanced biocomposites for applications in cell research, biomedicine, and bioenergy. This approach transforms living cells into functional materials and templates.

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Area of Science:

Biomaterials Science
Cell Engineering
Polymer Science

Background:

Biological cells possess intricate structures and chemistries valuable for creating advanced materials.
Cells serve as natural templates for engineering bioactive and biomorphic materials, devices, and systems.
Existing methods focus on polymer-directed cell surface engineering and intracellular functionalization.

Purpose of the Study:

To review recent advancements in creating cell-based biocomposites using polymer-directed strategies.
To discuss the applications of these biocomposites in diverse scientific fields.
To offer insights into future challenges and trends in this interdisciplinary area.

Main Methods:

Polymer grafting onto cell surfaces.
In situ hydrogelation for cell encapsulation.
Utilizing polymers as interfacial layers to bridge cells with other materials.

Main Results:

Polymeric materials can be effectively adopted by various cell types.
Successful integration of cells with functional materials via polymer interfaces.
Demonstrated bioaugmentation of living cells and transformation into templated materials.

Conclusions:

Polymer-directed strategies offer a powerful approach for constructing advanced cell-based biocomposites.
Cell-based biocomposites have significant potential in cell research, biomedicine, and bioenergy.
Further research is needed to address challenges and explore future trends in this field.