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Machine learning (ML) and epidemiology clash over causation. This paper argues for cautious ML application in public health, suggesting it can discover new concepts without strict causal inference constraints.

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Area of Science:

  • Epidemiology
  • Machine Learning
  • Causal Inference
  • Public Health

Background:

  • Epidemiology prioritizes causal inference, while machine learning (ML) research often does not.
  • A debate exists on whether ML in epidemiology should be causally constrained.
  • This paper examines the necessity of causal knowledge for predicting public health intervention outcomes.

Purpose of the Study:

  • To analyze the necessity of causal knowledge for predicting public health intervention outcomes.
  • To explore motivations for imposing causal constraints on ML in epidemiology.
  • To argue for a cautious approach to integrating ML in epidemiology.

Main Methods:

  • Disambiguation of motivations for causal constraints (definitional, metaphysical, epistemological, pragmatic).
  • Argumentation for a 'Proceed with caution' stance.
  • Exploration of ML's potential for discovering new epidemiological concepts.

Main Results:

  • Conviction of impossibility does not justify forbidding attempts.
  • All explored motivations for causal constraints support a 'Proceed with caution' approach.
  • ML can facilitate the discovery of new concepts through a process of reflective equilibrium.

Conclusions:

  • Causal inference can enforce pre-existing classifications, potentially hindering discovery.
  • ML, when not causally constrained, offers a method for discovering meaningful new concepts in epidemiology.
  • A cautious, iterative approach integrating ML can advance public health research.