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Updated: Oct 1, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Preoperative Workup for Patients with Pituitary Lesions
Alexandra White1, Erion Junior de Andrade2, Varun R Kshettry2
1Department of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 9500 Euclid Avenue, CA-51, Cleveland, OH 44195, USA.
Abstract:
The pituitary gland plays a vital role in hormonal regulation. Pituitary lesions include tumors, cysts, and inflammatory processes that require multidisciplinary care from endocrinologists, neuro-ophthalmologists, neurosurgeons, and otolaryngologists. Treatment is typically aimed at controlling hormonal hypersecretion, decompressing the optic apparatus, and reducing tumor volume, and surgery is a common first-line approach. In this article, we provide a background on the function of the pituitary gland, common pituitary lesions, and their clinical presentations, as well as a summary of the history and physical, laboratory testing, and imaging required for the workup of a pituitary lesion.
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