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Updated: Oct 1, 2025

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019
Angiosarcoma of a Femoropopliteal Bypass Thrombosed Vein Graft
Carlos Veterano1, Sérgio Teixeira1,2, Ivone Silva1,2,3
1Angiology and Vascular Surgery Department, 112085Centro Hospitalar Universitário do Porto, Porto, Portugal.
Background:
Angiosarcoma is a rare subtype of malignant vascular tumours which has been only anecdotally described in patients submitted to lower limb revascularization.
Case Presentation:
This paper reports a patient previously submitted to a femoropopliteal bypass using autologous great saphenous vein (GSV). Nine years after the initial surgery, a primary angiosarcoma of the thrombosed vein graft was diagnosed, requiring en bloc surgical resection. Rampant metastatic spread was documented despite primary tumour surgical resection with a dismal outcome within months.
Conclusions:
Malignant transformation of autologous vein for lower limb revascularization is extremely rare and anecdotally described in the literature. It is a poorly studied complication with an aggressive behaviour. This report further reinforces the need for early recognition of this pathology.
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