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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
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OPTN/SRTR 2020 Annual Data Report: Heart.

M Colvin1,2, J M Smith1,3, Y Ahn1

  • 1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|March 10, 2022
PubMed
Summary
This summary is machine-generated.

The COVID-19 pandemic impacted heart transplants in 2020, with fewer new listings but increased adult transplants. Adult post-transplant mortality shows a slight short-term rise but a long-term decrease.

Keywords:
End-stage heart failureheart transplanttransplant outcomesventricular assist device

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Area of Science:

  • Cardiology and Transplant Surgery
  • Public Health and Epidemiology

Background:

  • The implementation of a new adult heart allocation policy coincided with the COVID-19 pandemic.
  • The pandemic presented unique challenges to organ donation and transplantation processes.

Purpose of the Study:

  • To analyze the impact of the COVID-19 pandemic on heart transplant activity and outcomes.
  • To evaluate trends in adult and pediatric heart transplant listings and procedures.
  • To assess post-transplant mortality rates in adult and pediatric recipients.

Main Methods:

  • Retrospective analysis of heart transplant data from 2019 and 2020.
  • Comparison of transplant listings, procedures, and post-transplant mortality rates.
  • Stratification of data by recipient age (adult vs. pediatric) and time points (6 months, 1, 3, and 5 years post-transplant).

Main Results:

  • Adult heart transplants increased to 3715 in 2020, despite a slight decrease in total new listings.
  • Pediatric heart transplants declined in 2020.
  • Adult short-term post-transplant mortality saw a slight increase, while long-term mortality showed a downward trend.

Conclusions:

  • The adult heart allocation policy and pandemic influenced transplant volumes differently for adults and pediatric recipients.
  • While short-term survival post-adult heart transplant has slightly worsened, long-term outcomes continue to improve.
  • Ongoing monitoring is crucial to understand the long-term effects of the policy and pandemic on heart transplantation.