Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Image-Guided Thermal Ablation of Stage 1 Single and Multiple Primary Lung Carcinoma: Five-Year Outcomes.

Medical sciences (Basel, Switzerland)·2026
Same author

Hierarchical classification of immune cell transcriptomes at population-scale.

bioRxiv : the preprint server for biology·2026
Same author

Quantitative analysis of lung microwave ablation zone volume and shape.

European radiology experimental·2026
Same author

T-Cell Clonal Expansion in Peripheral Blood Following Interventional Radiology Procedures for Metastatic Liver Cancer.

Cancers·2026
Same author

The American Cancer Society National Lung Cancer Roundtable strategic plan: Challenges in clinical guideline recommendations for biomarker testing in lung cancer.

Cancer·2026
Same author

Yttrium-90 Radioembolization Versus Transarterial Embolization for Lung Carcinoid Hepatic Metastasis.

JTO clinical and research reports·2026

Related Experiment Video

Updated: Sep 30, 2025

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy
04:10

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Published on: July 19, 2024

840

Augmented fluoroscopy guided transbronchial pulmonary microwave ablation using a steerable sheath.

Mario Ghosn1, Ahmed S Elsakka1, Fourat Ridouani1

  • 1Interventional Radiology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Translational Lung Cancer Research
|March 14, 2022
PubMed
Summary

Transbronchial microwave ablation (MWA) using augmented fluoroscopy and a steerable sheath is a feasible and accurate technique for treating lung targets without a bronchoscope. This novel approach enhances precision in minimally invasive procedures.

Keywords:
Ablation techniquesaugmented fluoroscopycone-beam computed tomography (CBCT)lung neoplasmssteerable sheath

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.6K

Related Experiment Videos

Last Updated: Sep 30, 2025

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy
04:10

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Published on: July 19, 2024

840
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.6K

Area of Science:

  • Interventional Pulmonology
  • Medical Imaging
  • Minimally Invasive Surgery

Background:

  • Transbronchial microwave ablation (MWA) shows promise for novel therapies.
  • Current bronchoscopy and navigation lack real-time image guidance for probe delivery and have limited distal maneuverability.
  • Cone-beam computed tomography (CBCT) augmented fluoroscopy with steerable sheaths may address these limitations.

Purpose of the Study:

  • To evaluate the feasibility and accuracy of transbronchial MWA.
  • To assess augmented fluoroscopy guidance using a steerable sheath without a bronchoscope.

Main Methods:

  • Prospective study in pigs under general anesthesia.
  • Percutaneous placement of synthetic lung targets.
  • Airway navigation using CBCT-derived data overlaid on live fluoroscopy.
  • Endobronchial navigation solely under augmented fluoroscopy with a steerable sheath and MWA probe.

Main Results:

  • Eighteen targets were ablated in 9 pigs with a median target diameter of 9 mm.
  • Median needle-target center distance was 2 mm; accuracy varied by lung lobe.
  • No severe complications or pneumothorax occurred; minor rib fractures resolved.

Conclusions:

  • Transbronchial MWA guided by augmented fluoroscopy and a steerable sheath is feasible.
  • This technique demonstrates accuracy in reaching targets without a bronchoscope.