Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulse-on-Demand Operation for Precise High-Speed UV Laser Microstructuring.

Micromachines·2023
Same author

Method for controlled tissue theranostics using a single tunable laser source.

Biomedical optics express·2021
Same author

Cavitation induced by shock wave focusing in eye-like experimental configurations.

Biomedical optics express·2020
Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026
Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026
Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026
Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026
Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026
Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026
See all related articles

Related Experiment Video

Updated: Sep 30, 2025

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

11.8K

Microbubble dynamics and jetting near tissue-phantom biointerfaces.

Jaka Mur1,2, Vid Agrež1, Jaka Petelin1

  • 1University of Ljubljana, Faculty of Mechanical Engineering, Aškerčeva 6, SI-1000 Ljubljana, Slovenia.

Biomedical Optics Express
|March 14, 2022
PubMed
Summary
This summary is machine-generated.

Precise cavitation bubble jetting near biointerfaces enables targeted microsurgery. Bubbles create localized jets that penetrate tissue phantoms below a critical distance, enhancing drug delivery potential.

More Related Videos

Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis
05:31

Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis

Published on: September 5, 2020

6.0K
Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces
08:05

Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

Published on: September 9, 2022

2.5K

Related Experiment Videos

Last Updated: Sep 30, 2025

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

11.8K
Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis
05:31

Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis

Published on: September 5, 2020

6.0K
Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces
08:05

Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

Published on: September 9, 2022

2.5K

Area of Science:

  • Physics
  • Biomedical Engineering
  • Acoustics

Background:

  • Cavitation bubble dynamics are crucial for microsurgery and drug delivery.
  • Near-surface interactions govern bubble jetting behavior.
  • Understanding boundary effects is key to controlling cavitation.

Purpose of the Study:

  • To investigate boundary effects on cavitation bubble dynamics and jetting.
  • To observe and measure jetting behavior near tissue-phantom biointerfaces.
  • To elucidate the mechanism of boundary poration.

Main Methods:

  • Time-resolved optical microscopy was used to observe cavitation bubble dynamics.
  • Experiments were conducted with varying tissue-phantom surface densities and Young's modulus.
  • Bubble-boundary interactions were analyzed at critical distances.

Main Results:

  • Boundary effects significantly influence cavitation bubble dynamics and morphology.
  • A critical distance (around γ = 1.0) was identified for jet penetration.
  • Highly localized jets (few micrometer diameter) were observed to penetrate tissue-phantoms.

Conclusions:

  • Cavitation jetting near biointerfaces can achieve precise tissue poration.
  • This mechanism holds promise for targeted drug delivery and microsurgery.
  • Controlling bubble-boundary interactions is essential for therapeutic applications.